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Mcl‐1 targeting could be an intriguing perspective to cure cancer

24 May 2018

Abstract excerpt

The Bcl-2 family, which plays important roles in controlling cancer development, is divided into antiapoptotic and proapoptotic members. The change in the balance between these members governs the life and death of the cells. Mcl-1 is an antiapoptotic member of this family and its distribution in normal and cancerous tissues strongly differs from that of Bcl-2. In human cancers, where upregulation of...

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PMID: 29797573
DOI: 10.1002/jcp.26786

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