Article
Rs548234 polymorphism at PRDM1-ATG5 region susceptible to rheumatoid arthritis in Caucasians is not associated with rheumatoid arthritis in Chinese Han population.
Chinese medical journal - 1 Sept 2011
Lu Xiao-Lan, Zhou Xu-Jie, Guo Jian-Ping, Jia Ru-Lin, Zhao Yi, Jiang Quan, Liu Xiang-Yuan, Liu Yi, Sun Ling-Yun, Zhang Hong, Li Zhan-Guo
Abstract excerpt
BACKGROUND: A previous study has shown that rs548234 polymorphism at PRDM1-ATG5 region is associated with rheumatoid arthritis (RA) in Caucasian populations. The aim of this study was to investigate the effect of rs548234 polymorphism at PRDM1-ATG5 region on susceptibility to RA in Chinese Han population. METHODS: We genotyped 848 RA patients and 1431 matched healthy controls for rs548234 single-nucleotide...
Read the complete abstract on PubMed