A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis.

doi:10.1155/2014/834831

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Article

A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis.

Mediators of inflammation - 1 Jan 2014

Yen Jeng-Hsien, Chang Che-Mai, Hsu Yu-Wen, Lee Chih-Hung, Wu Mei-Shin, Hwang Daw-Yang, Chen Ben-Kuen, Liao Hsien-Tzung, Wu Man-Tzu Marcie, Chang Wei-Chiao

Abstract excerpt

Rheumatoid arthritis (RA), a chronic inflammatory disease usually occurring in synovial tissues and joints, is highly associated with genetic and environmental factors. ORAI1, a gene related to cellular immune system, has been shown to be involved in the pathogenesis of chronic inflammatory diseases and immune diseases. To identify whether ORAI1 gene contributes to RA susceptibility, we enrolled 400 patients with...

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Identifiers

PMID: 24808640
DOI: 10.1155/2014/834831
PMCID: PMC3997980

Genes

ORAI1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.