Article
Role of APOBEC3H in the Viral Control of HIV Elite Controller Patients.
International journal of medical sciences - 1 Jan 2018
Benito José M, Hillung Julia, Restrepo Clara, Cuevas José M, León Agathe, Ruiz-Mateos Ezequiel, Palacios-Muñoz Rosario, Górgolas Miguel, Sanjuán Rafael, Rallón Norma
Abstract excerpt
Background APOBEC3H (A3H) gene presents variation at 2 positions (rs139297 and rs79323350) leading to a non-functional protein. So far, there is no information on the role played by A3H in spontaneous control of HIV. The aim of this study was to evaluate the A3H polymorphisms distribution in a well-characterized group of Elite Controller (EC) subjects. Methods We analyzed the genotype distribution of two...
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