Article
Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region.
BMC infectious diseases - 25 Jul 2020
Gomes Samara Tatielle Monteiro, da Silva Graça Amoras Ednelza, Gomes Érica Ribeiro, Queiroz Maria Alice Freitas, Júnior Edivaldo Costa Sousa, de Vasconcelos Massafra Janaína Mota, da Silva Lemos Poliana, Júnior João Lídio Vianez, Ishak Ricardo, Vallinoto Antonio Carlos Rosário
Abstract excerpt
BACKGROUND: Human immunodeficiency virus (HIV-1) infection is characterized by high viral replication and a decrease in CD4+ T cells (CD4+TC), resulting in AIDS, which can lead to death. In elite controllers and viremia controllers, viral replication is naturally controlled, with maintenance of CD4+TC levels without the use of antiretroviral therapy (ART). METHODS: The aim of the present study was to describe...
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