Article
APOBEC3H polymorphisms associated with the susceptibility to HIV-1 infection and AIDS progression in Japanese.
Immunogenetics - 1 Apr 2015
Sakurai Daisuke, Iwatani Yasumasa, Ohtani Hitoshi, Naruse Taeko K, Terunuma Hiroshi, Sugiura Wataru, Kimura Akinori
Abstract excerpt
Human APOBEC3H (A3H) is a member of APOBEC3 cytidine deaminase family that potently restricts HIV-1 replication. Because A3H is genetically divergent with different intracellular stability and anti-HIV-1 activity in vitro, we investigated a possible association of A3H with susceptibility to HIV-1 infection and disease progression in Japanese populations. A total of 191 HIV-1-infected individuals (HIV group), 93...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
