Article
Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder.
Psychiatry research - 30 Aug 2010
Gałecki Piotr, Smigielski Janusz, Florkowski Antoni, Bobińska Kinga, Pietras Tadeusz, Szemraj Janusz
Abstract excerpt
Reactive oxygen species (ROS) may contribute to the pathogenesis of depressive disorder (DD). Functional genetic polymorphisms of manganese superoxide dismutase (MnSOD) are candidates for DD susceptibility. The study examined the relationship between MnSOD gene polymorphisms (Ala-9Val, Ile-58Thr) and DD in the Polish population. The association study was conducted in a case-control design in DD patients (n=149)...
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