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Article

Variation of genes encoding KAT1, AADAT and IDO1 as a potential risk of depression development.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Aug 2018

Wigner Paulina, Czarny Piotr, Synowiec Ewelina, Bijak Michał, Talarowska Monika, Galecki Piotr, Szemraj Janusz, Sliwinski Tomasz

Abstract excerpt

Numerous data suggests that the disorders of tryptophan catabolites (TRYCATs) pathway, including a decreased level of tryptophan or evaluated concentration of harmful TRYCATs -kynurenine, quinolinic acid, 3-hydroxyanthranilic acid, 3-hydroxytryptophan - may cause the occurrence of DD symptoms. In this work, we assessed the relationship between single-nucleotide polymorphisms (SNPs) of KAT1, KAT2 and IDO1 gene...

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Identifiers

PMID: 29777939
DOI: 10.1016/j.eurpsy.2018.05.001

Genes

AADAT
IDO1

Provenance

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