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Article

A Metabolomics Pilot Study on Desmoid Tumors and Novel Drug Candidates.

Scientific reports - 12 Jan 2018

Mercier Kelly A, Al-Jazrawe Mushriq, Poon Raymond, Acuff Zachery, Alman Benjamin

Abstract excerpt

Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors that lack the ability to metastasize. There are no directed therapies or standard treatment plan, and chemotherapeutics, radiation, and surgery often have temporary effects. The majority of desmoid tumors are related to T41A and S45F mutations of the beta-catenin encoding gene (CTNNB1). Using broad spectrum metabolomics, differences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Screening Assays, Antitumor

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Source

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Identifiers

PMID: 29330550
DOI: 10.1038/s41598-017-18921-7
PMCID: PMC5766559

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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