Article
Uveal Melanoma Patients Have a Distinct Metabolic Phenotype in Peripheral Blood.
International journal of molecular sciences - 7 Mar 2023
de Bruyn Daniël P, Bongaerts Michiel, Bonte Ramon, Vaarwater Jolanda, Meester-Smoor Magda A, Verdijk Robert M, Paridaens Dion, Naus Nicole C, de Klein Annelies, Ruijter George J G, Kiliç Emine, Brosens Erwin
Abstract excerpt
Uveal melanomas (UM) are detected earlier. Consequently, tumors are smaller, allowing for novel eye-preserving treatments. This reduces tumor tissue available for genomic profiling. Additionally, these small tumors can be hard to differentiate from nevi, creating the need for minimally invasive detection and prognostication. Metabolites show promise as minimally invasive detection by resembling the biological...
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