Article
Establishment and characterization of NCC-DSM1-C1: a novel cell line derived from a patient with desmoid fibromatosis.
Human cell - 1 Mar 2023
Akiyama Taro, Yoshimatsu Yuki, Noguchi Rei, Sin Yooksil, Osaki Julia, Ono Takuya, Adachi Yuki, Tsuchiya Ryuto, Toda Yu, Kobayashi Eisuke, Kojima Naoki, Yoshida Akihiko, Ohtori Seiji, Kawai Akira, Kondo Tadashi
Abstract excerpt
Desmoid fibromatosis (DSM) is a rare, locally aggressive mesenchymal tumor genetically characterized by mutations in the CTNNB1 gene. A local control rate of up to 65‒80% for DSM is achieved with multiple modality treatments, including watchful monitoring, radiation therapy, chemotherapy, and surgery. However, several variables, such as age < 30 years, extremity tumor location, and tumor size of > 10 cm in...
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