Article
A Comparison of Real-Time Polymerase Chain Reaction Assays for the Detection of Antimicrobial Resistance Markers and Sequence Typing From Clinical Nucleic Acid Amplification Test Samples and Matched Neisseria gonorrhoeae Culture.
Sexually transmitted diseases - 1 Feb 2018
Peterson Shelley W, Martin Irene, Demczuk Walter, Hoang Linda, Wylie John, Lefebvre Brigitte, Labbé Annie-Claude, Naidu Prenilla, Haldane David, Mulvey Michael R
Abstract excerpt
Real-time polymerase chain reaction (PCR) assays to detect antimicrobial resistance-associated mutations were tested on Neisseria gonorrhoeae-positive clinical samples with matched isolates. Of the nucleic acid amplification tests/cultures, 87.7% (64/73), 98.6% (72/73), and 98.4% (62/63) predicted cephalosporin, ciprofloxacin, and azithromycin susceptibilities, respectively. N. gonorrhoeae multiantigen sequence...
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