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Wild-Type Gyrase A Genotype of Neisseria gonorrhoeae Predicts In Vitro Susceptibility to Ciprofloxacin: A Systematic Review of the Literature and Meta-Analysis.

Sexually transmitted diseases - 1 May 2017

Allan-Blitz Lao-Tzu, Wang Xiaoyan, Klausner Jeffrey D

Abstract excerpt

Multidrug-resistant Neisseria gonorrhoeae infections have been declared 1 of the top 3 urgent threats to public health. Approaches to combat resistance include targeted therapy with antibiotics previously thought to be ineffective, made possible by rapid molecular assays to predict susceptibility. Previous studies have associated the gyrase A (gyrA) gene of N. gonorrhoeae with in vitro resistance to...

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Anti-Bacterial Agents
Ciprofloxacin
DNA Gyrase
Drug Resistance, Bacterial
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neisseria gonorrhoeae

Polymerase Chain Reaction

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Identifiers

PMID: 28407640
DOI: 10.1097/OLQ.0000000000000591
PMCID: PMC5407314

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