Article
Molecular Assay for Detection of Genetic Markers Associated with Decreased Susceptibility to Cephalosporins in Neisseria gonorrhoeae.
Journal of clinical microbiology - 1 Jul 2015
Peterson S W, Martin I, Demczuk W, Bharat A, Hoang L, Wylie J, Allen V, Lefebvre B, Tyrrell G, Horsman G, Haldane D, Garceau R, Wong T, Mulvey M R
Abstract excerpt
The incidence of antimicrobial-resistant Neisseria gonorrhoeae continues to rise in Canada; however, antimicrobial resistance data are lacking for approximately 70% of gonorrhea infections that are diagnosed directly from clinical specimens by nucleic acid amplification tests (NAATs). We developed a molecular assay for surveillance use to detect mutations in genes associated with decreased susceptibility to...
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