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Article

Direct real-time PCR-based detection of Neisseria gonorrhoeae 23S rRNA mutations associated with azithromycin resistance.

The Journal of antimicrobial chemotherapy - 1 Dec 2015

Trembizki Ella, Buckley Cameron, Donovan Basil, Chen Marcus, Guy Rebecca, Kaldor John, Lahra Monica M, Regan David G, Smith Helen, Ward James, Whiley David M

Abstract excerpt

OBJECTIVES: Surveillance for Neisseria gonorrhoeae azithromycin resistance is of growing importance given increasing use of ceftriaxone and azithromycin dual therapy for gonorrhoea treatment. In this study, we developed two real-time PCR methods for direct detection of two key N. gonorrhoeae 23S rRNA mutations associated with azithromycin resistance. METHODS: The real-time PCR assays, 2611-PCR and 2059-PCR,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26338048
DOI: 10.1093/jac/dkv274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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