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Article

Simultaneous Detection of Neisseria gonorrhoeae and Fluoroquinolone Resistance Mutations to Enable Rapid Prescription of Oral Antibiotics.

Sexually transmitted diseases - 1 Apr 2020

de Korne-Elenbaas Jolinda, Pol Arno, Vet Jacqueline, Dierdorp Mirjam, van Dam Alje P, Bruisten Sylvia M

Abstract excerpt

BACKGROUND: Absence of rapid antimicrobial resistance testing of Neisseria gonorrhoeae (Ng) hinders personalized antibiotic treatment. To enable rapid ciprofloxacin prescription, a real-time polymerase chain reaction (PCR) for simultaneous detection of Ng and fluoroquinolone resistance-associated gyrA-S91F mutation was evaluated. METHODS: Analytical NG quantitative PCR kit (NYtor BV) performance was assessed on...

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Identifiers

PMID: 32022739
DOI: 10.1097/OLQ.0000000000001141
PMCID: PMC7077958

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