Article
CR1 levels and gene polymorphisms exhibit differential association with falciparum malaria in regions of varying disease endemicity.
Human immunology - 1 Apr 2009
Sinha Swapnil, Jha Ganga N, Anand Prerna, Qidwai Tabish, Pati Sudhanshu S, Mohanty Sanjib, Mishra Saroj K, Tyagi Prajesh K, Sharma Surya K, Venkatesh Vimala, Habib Saman
Abstract excerpt
Complement receptor 1 (CR1/CD35) levels on erythrocytes and related CR1 polymorphisms have been associated with response to falciparum malaria in populations inhabiting malaria-endemic regions. Differences in disease association profiles of its low expression alleles have been observed in populations from different regions of the world. We analyzed the influence of CR1 levels and associated SNPs on...
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