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Article

Methods to Determine Mutational Trajectories After Experimental Evolution of Antibiotic Resistance.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Huseby Douglas L, Hughes Diarmaid

Abstract excerpt

The evolution of bacterial resistance to antibiotics by mutation within the genome (as distinct from horizontal gene transfer of new material into a genome) could occur in a single step but is usually a multistep process. Resistance evolution can be studied in laboratory environments by serial passage of bacteria in liquid culture or on agar, with selection at constant, or varying, concentrations of drug. Whole...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29322462
DOI: 10.1007/978-1-4939-7638-6_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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