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Article

Evaluation of a developmental hierarchy for breast cancer cells to assess risk-based patient selection for targeted treatment

4 Jan 2018

Abstract excerpt

This study proposes that a novel developmental hierarchy of breast cancer (BC) cells (BCCs) could predict treatment response and outcome. The continued challenge to treat BC requires stratification of BCCs into distinct subsets. This would provide insights on how BCCs evade treatment and adapt dormancy for decades. We selected three subsets, based on the relative expression of octamer-binding transcription factor...

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PMID: 29321622
DOI: 10.1038/s41598-017-18834-5

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