Article
Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.
Genes & development - 15 Nov 2009
Visvader Jane E
Abstract excerpt
The epithelium of the mammary gland exists in a highly dynamic state, undergoing dramatic morphogenetic changes during puberty, pregnancy, lactation, and regression. The recent identification of stem and progenitor populations in mouse and human mammary tissue has provided evidence that the mammary epithelium is organized in a hierarchical manner. Characterization of these normal epithelial subtypes is an...
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