Article
Age-Related Clusters and Favorable Immune Phenotypes in Young Breast Cancer Patients.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2024
Ingebriktsen Lise Martine, Svanøe Amalie Abrahamsen, Myrmel Sæle Anna Kristine, Humlevik Rasmus Olai Collett, Toska Karen, Kalvenes May Britt, Aas Turid, Heie Anette, Askeland Cecilie, Knutsvik Gøril, Stefansson Ingunn Marie, Akslen Lars Andreas, Hoivik Erling Andre, Wik Elisabeth
Abstract excerpt
Breast cancer (BC) patients aged <40 years at diagnosis experience aggressive disease and poorer survival compared with women diagnosed with BC at 40 to 49 years, but the age-related biology is described to little extent. Here, we explored transcriptional alterations in BC to gain better understanding of age-related tumor biology. We studied a subset of the Bergen in-house cohort (n = 127; age range, 26-49 years)...
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