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Understanding breast cancer stem cell heterogeneity: time to move on to a new research paradigm

23 Jul 2013

Abstract excerpt

Human breast cancer (BC) is one of the leading causes of death for women worldwide, and is characterized by a group of highly heterogeneous lesions. The morphological and biomolecular heterogeneity of BC cells, accompanied by dynamic plasticity of the BC microenvironment and the presence of stem-like cells, make tumor categorization an urgent and demanding task.The major limitations in BC research include the...

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PMID: 23879988
DOI: 10.1186/1741-7015-11-169

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