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Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis

4 Jan 2018

Abstract excerpt

The significance of mitochondrial metabolism in cancer cells has recently been gaining attention. Among other findings, One-carbon folate metabolism has been reported to be closely associated with cellular characteristics in cancer. To study molecular targets for efficient cancer therapy, we investigated the association between the expressions of genes that code enzymes involved in one-carbon metabolism and...

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PMID: 29321536
DOI: 10.1038/s41598-017-18456-x

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