Article

Up-Regulation of MTHFD2 is Associated With Clinicopathological Characteistics and Poor Survival in Ovarian Cancer, Possibly By Regulating MOB1A Signaling

2021-09-29

Abstract excerpt

<h4>Background: </h4> MTHFD2 is a folate-coupled metabolic enzyme, which has been proved to participant in the metabolic reprogramming and tumor cell-sustaining proliferative capacity. However, the function of MTHFD2 in the development of ovarian cancer and its potential molecular mechanisms is still unclear. <h4>Materials: </h4> and methods: The expression, various mutations, prognosis, and related network signal...

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Literature Corpus work: 759fa071-7980-5ed4-be8c-725a2d0c97e3
DOI: 10.21203/rs.3.rs-929562/v1

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