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Article

An Autophagy-Independent Role for ATG41 in Sulfur Metabolism During Zinc Deficiency.

Genetics - 1 Mar 2018

Bucci Michael D, Weisenhorn Erin, Haws Spencer, Yao Zhiyuan, Zimmerman Ginelle, Gannon Molly, Taggart Janet, Lee Traci, Klionsky Daniel J, Russell Jason, Coon Joshua, Eide David J

Abstract excerpt

The Zap1 transcription factor of Saccharomyces cerevisiae is a key regulator in the genomic responses to zinc deficiency. Among the genes regulated by Zap1 during zinc deficiency is the autophagy-related gene ATG41 Here, we report that Atg41 is required for growth in zinc-deficient conditions, but not when zinc is abundant or when other metals are limiting. Consistent with a role for Atg41 in macroautophagy, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29321173
DOI: 10.1534/genetics.117.300679
PMCID: PMC5844326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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