Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cooperative Function of Atg8- and TORC1-Mediated Activities in Yeast.

Yeast (Chichester, England) - 1 Sept 2025

Oba Yumiko, Higuchi Miyuki, Takahashi Naoka, Katsuta Haruko, Koike Naoki, Ushimaru Takashi, Kimura Yoko

Abstract excerpt

The target of rapamycin complex 1 (TORC1) protein kinase plays an important role in regulating various cellular activities in response to nutrient availability. In this study, an autophagy-related protein 8 (atg8) mutant of Saccharomyces cerevisiae was highly sensitive to cellular processes in which TORC1 activity was inhibited by rapamycin treatment or by a mutated allele of KOG1 which encodes a subunit of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Autophagy-Related Protein 8 Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Sirolimus

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 40568955
DOI: 10.1002/yea.4003
PMCID: PMC12511908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cooperative Function of Atg8- and TORC1-Mediated Activities in Yeast.PMID 40568955Read ↗

An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation.Semantic proximity Read ↗

Bidirectional regulation between TORC1 and autophagy in Saccharomyces cerevisiae.Semantic proximity Read ↗

Target of Rapamycin (TOR) in Nutrient Signaling and Growth ControlSemantic proximity Read ↗

Structure-based engineering of Tor complexes uncovers different roles of two types of yeast TORC1sSemantic proximity Read ↗

TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Interrelationships among Atg proteins during autophagy in Saccharomyces cerevisiae.Semantic proximity Read ↗

ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase.Semantic proximity Read ↗

Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy.Semantic proximity Read ↗

Manganese is a Physiologically Relevant TORC1 Activator in Yeast and MammalsSemantic proximity Read ↗

Autophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiae.Semantic proximity Read ↗

Hyper-activation of the target of rapamycin (Tor) kinase 1 decreases intracellular glutathione content in Saccharomyces cerevisiae as revealed by LC-MS/MS analysis.Semantic proximity Read ↗

An Autophagy-Independent Role for ATG41 in Sulfur Metabolism During Zinc Deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.