Restricted glycolysis is a primary cause of the reduced growth rate of zinc-deficient yeast cells.

Abstract excerpt

Zinc is required for many critical processes, including intermediary metabolism. In Saccharomyces cerevisiae, the Zap1 activator regulates the transcription of ∼80 genes in response to Zn supply. Some Zap1-regulated genes are Zn transporters that maintain Zn homeostasis, while others mediate adaptive responses that enhance fitness. One adaptive response gene encodes the 2-cysteine peroxiredoxin Tsa1, which is...

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• Fructose-Bisphosphate Aldolase
• Gene Expression Regulation, Fungal
• Glycolysis
• Peroxidases
• Peroxiredoxins