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Article

MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours.

British journal of cancer - 1 Jan 2018

Garcia-Dios Diego A, Levi Dina, Shah Vandna, Gillett Cheryl, Simpson Michael A, Hanby Andrew, Tomlinson Ian, Sawyer Elinor J

Abstract excerpt

BACKGROUND: MED12 and TERT promoter mutations have been shown to be the most common somatic mutations in phyllodes tumours (PTs). The aims of this study were to determine the frequency of these mutations in recurrent PTs, assess whether TERT promoter mutations could be helpful in distinguishing fibroadenomas (FAs) from PTs and identify novel mutations that may be driving malignant progression. METHODS: MED12 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

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Source

Open in PubMed Open full text

Identifiers

PMID: 29315289
DOI: 10.1038/bjc.2017.450
PMCID: PMC5785756

Genes

TERT
MED12
RBM15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours.PMID 29315289Read ↗

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