Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Periductal Stromal Tumor of the Breast with a TERT Promoter Mutation: First Case Report with Comprehensive Molecular Analysis.

International journal of surgical pathology - 1 Dec 2023

Anderson Blaire, Marotti Jonathan D, Lefferts Joel A, Muller Kristen E

Abstract excerpt

The molecular pathogenesis of breast fibroepithelial tumors continues to be elucidated. Recently, highly recurrent MED12 mutations arising in exon 2 at codon 44 were discovered in fibroadenomas and phyllodes tumors. In addition, a high prevalence of TERT promoter mutations in two hotspots (124 and 126 bp upstream from the translation start site) was discovered in up to 65% of phyllodes tumors. Breast periductal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mediator Complex

Share to Mutation

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 36823780
DOI: 10.1177/10668969231157306
PMCID: PMC10942729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Periductal Stromal Tumor of the Breast with a TERT Promoter Mutation: First Case Report with Comprehensive Molecular Analysis.PMID 36823780Read ↗

Association of clinicopathological features and prognosis of TERT alterations in phyllodes tumor of breast.Semantic proximity Read ↗

Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression.Semantic proximity Read ↗

TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast.Semantic proximity Read ↗

MED12, TERT and RARA in fibroepithelial tumours of the breast.Semantic proximity Read ↗

Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathwaysSemantic proximity Read ↗

Recurrent MED12 exon 2 mutations in benign breast fibroepithelial lesions in adolescents and young adultsSemantic proximity Read ↗

[Pathological features and clinicopathological significance of TERT promoter mutation in breast fibroepithelial tumors without definite diagnosis].Semantic proximity Read ↗

Genetic and Clinical Characteristics of Phyllodes Tumors of the BreastSemantic proximity Read ↗

MED12 exon 2 and TERT promoter mutations in primary and recurrent breast fibroepithelial lesions.Semantic proximity Read ↗

Droplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations.Semantic proximity Read ↗

MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours.Semantic proximity Read ↗

Molecular pathology of phyllodes tumours of the breast-much more than MED12.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.