Article
Analysis of recurrent molecular alterations in phyllodes tumour of breast: insights into prognosis and pathogenesis.
Pathology - 1 Oct 2022
Tsang Julia Y, Shao Yan, Poon Ivan K, Ni Yun-Bi, Kwan Johnny S, Chow Chit, Shea Ka-Ho, Tse Gary M
Abstract excerpt
Phyllodes tumour (PT) of breast is a rare biphasic neoplasm. Recent next generation sequencing analyses had revealed novel genetic alterations in PT but lacked a further characterisation of their relationship to different PT features and outcome. Here, using targeted sequencing, we examined a panel of 90 recurrently altered or cancer related genes in 88 PT samples (including 49 benign, 25 borderline and 14...
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