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Article

Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform.

Sensors (Basel, Switzerland) - 5 Jan 2018

Guarnaccia Maria, Iemmolo Rosario, San Biagio Floriana, Alessi Enrico, Cavallaro Sebastiano

Abstract excerpt

The KRAS oncogene is involved in the pathogenesis of several types of cancer, particularly colorectal cancer (CRC). The most frequent mutations in this gene are associated with poor survival, increased tumor aggressiveness and resistance to therapy with anti-epidermal growth factor receptor (EGFR) antibodies. For this reason, KRAS mutation testing has become increasingly common in clinical practice for...

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Identifiers

PMID: 29304017
DOI: 10.3390/s18010131
PMCID: PMC5795341

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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