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Article

Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping.

Sensors (Basel, Switzerland) - 11 Apr 2017

Guarnaccia Maria, Iemmolo Rosario, Petralia Salvatore, Conoci Sabrina, Cavallaro Sebastiano

Abstract excerpt

Colorectal cancer (CRC) is an aggressive human malignancy with a complex genomic landscape harboring KRAS mutations. In 40%-60% of patients with CRC, constantly active KRAS proteins affect the prognosis, surgical strategy, and clinical benefit from therapy with anti-epidermal growth factor receptor (EGFR) agents. For this reason, there is a greater demand for minimally-invasive diagnostic devices to characterize...

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Identifiers

PMID: 28398227
DOI: 10.3390/s17040831
PMCID: PMC5422192

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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