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Article

Genetic basis for relapse rate in multiple sclerosis: Association with LRP2 genetic variation.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Nov 2018

Hilven Kelly, Vandebergh Marijne, Smets Ide, Mallants Klara, Goris An, Dubois Bénédicte

Abstract excerpt

BACKGROUND: In contrast to successes for multiple sclerosis (MS) susceptibility, the genetic basis for clinical heterogeneity remains largely unresolved. OBJECTIVES: We investigate the first reported genetic association with relapse rate. METHODS: We genotyped variant rs12988804 in LRP2 in a homogeneous study population of 527 Belgian MS patients with 970 documented relapses. RESULTS: The rs12988804*T allele is...

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Source

Identifiers

PMID: 29303040
DOI: 10.1177/1352458517749894

Genes

LRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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