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Article

Genetic Variation in WNT9B Increases Relapse Hazard in Multiple Sclerosis.

Annals of neurology - 1 May 2021

Vandebergh Marijne, Andlauer Till F M, Zhou Yuan, Mallants Klara, Held Friederike, Aly Lilian, Taylor Bruce V, Hemmer Bernhard, Dubois Bénédicte, Goris An

Abstract excerpt

OBJECTIVE: Many multiple sclerosis (MS) genetic susceptibility variants have been identified, but understanding disease heterogeneity remains a key challenge. Relapses are a core feature of MS and a common primary outcome of clinical trials, with prevention of relapses benefiting patients immediately and potentially limiting long-term disability accrual. We aim to identify genetic variation associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33704824
DOI: 10.1002/ana.26061
PMCID: PMC8252032

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