Article
The NLR family pyrin domain-containing 11 protein contributes to the regulation of inflammatory signaling.
The Journal of biological chemistry - 23 Feb 2018
Ellwanger Kornelia, Becker Emily, Kienes Ioannis, Sowa Anna, Postma Yvonne, Cardona Gloria Yamel, Weber Alexander N R, Kufer Thomas A
Abstract excerpt
Mammalian Nod-like receptor (NLR) proteins contribute to the regulation and induction of innate and adaptive immunity in mammals, although the function of about half of the currently identified NLR proteins remains poorly characterized. Here we analyzed the function of the primate-specific NLRP11 gene product. We show that NLRP11 is highly expressed in immune cells, including myeloid cells, B cells, and some B...
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