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NOD-like Receptor Signaling Pathway in Gastrointestinal Inflammatory Diseases and Cancers

25 Sept 2023

Abstract excerpt

Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are intracellular proteins with a central role in innate and adaptive immunity. As a member of pattern recognition receptors (PRRs), NLRs sense specific pathogen-associated molecular patterns, trigger numerous signaling pathways and lead to the secretion of various cytokines. In recent years, cumulative studies have revealed the significant...

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PMID: 37833958
DOI: 10.3390/ijms241914511

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