Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers.

BMC cancer - 4 Jan 2018

Kikulska Agnieszka, Rausch Tobias, Krzywinska Ewa, Pawlak Magdalena, Wilczynski Bartek, Benes Vladimir, Rutkowski Piotr, Wilanowski Tomasz

Abstract excerpt

BACKGROUND: The Grainyhead-like (GRHL) transcription factors have been linked to many different types of cancer. However, no previous study has attempted to investigate potential correlations in expression of different GRHL genes in this context. Furthermore, there is very little information concerning damaging mutations and/or single nucleotide polymorphisms in GRHL genes that may be linked to cancer. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Gene Expression Regulation, Neoplastic

Share to MicroRNAs

Share to Repressor Proteins

Share to Skin Neoplasms

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29301499
DOI: 10.1186/s12885-017-3943-8
PMCID: PMC5755140

Genes

GRHL3
GRHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers.PMID 29301499Read ↗

Grainyhead-like (Grhl) Target Genes in Development and CancerSemantic proximity Read ↗

Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanismSemantic proximity Read ↗

Threonine 454 phosphorylation in Grainyhead-like 3 is important for its function and regulation by the p38 MAPK pathway.Semantic proximity Read ↗

Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome.Semantic proximity Read ↗

Genome-wide identification of binding sites of GRHL2 in luminal-like and basal A subtypes of breast cancerSemantic proximity Read ↗

The long non‐coding RNA LINC00941 and SPRR5 are novel regulators of human epidermal homeostasisSemantic proximity Read ↗

Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.Semantic proximity Read ↗

Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression.Semantic proximity Read ↗

Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes.Semantic proximity Read ↗

Grainyhead-like transcription factors in cancer - Focus on recent developments.Semantic proximity Read ↗

Common genetic polymorphisms contribute to the association between chronic lymphocytic leukaemia and non-melanoma skin cancer.Semantic proximity Read ↗

Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.