Article
Ram locus is a key regulator to trigger multidrug resistance in Enterobacter aerogenes.
Journal of medical microbiology - 1 Feb 2018
Molitor Alexander, James Chloë E, Fanning Séamus, Pagès Jean-Marie, Davin-Regli Anne
Abstract excerpt
PURPOSE: Several genetic regulators belonging to AraC family are involved in the emergence of MDR isolates of E. aerogenes due to alterations in membrane permeability. Compared with the genetic regulator Mar, RamA may be more relevant towards the emergence of antibiotic resistance. METHODOLOGY: Focusing on the global regulators, Mar and Ram, we compared the amino acid sequences of the Ram repressor in 59 clinical...
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