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Article

ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium.

Antimicrobial agents and chemotherapy - 1 Jul 2008

Abouzeed Yousef M, Baucheron Sylvie, Cloeckaert Axel

Abstract excerpt

In the sequenced genome of Salmonella enterica serovar Typhimurium strain LT2, an open reading frame (STM0580) coding for a putative regulatory protein of the TetR family is found upstream of the ramA gene. Overexpression of ramA results in increased expression of the AcrAB efflux pump and, consequently, multidrug resistance (MDR) in several bacterial species. The inactivation of the putative regulatory protein...

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Identifiers

PMID: 18443112
DOI: 10.1128/AAC.00084-08
PMCID: PMC2443889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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