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Article

Differential impact of ramRA mutations on both ramA transcription and decreased antimicrobial susceptibility in Salmonella Typhimurium.

The Journal of antimicrobial chemotherapy - 1 Mar 2016

Fàbrega Anna, Ballesté-Delpierre Clara, Vila Jordi

Abstract excerpt

OBJECTIVES: This study was focused on analysing the heterogeneity of mutations occurring in the regulators of efflux-mediated MDR in Salmonella Typhimurium. Moreover, the impact of such mutations on impairing the transcription of ramA, acrB, tolC and acrF was also assessed as was the impact on the resistance or decreased susceptibility phenotype. METHODS: Strains were selected in vitro under increasing...

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PMID: 26679248
DOI: 10.1093/jac/dkv410

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