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Article

Gsw-fi: a GLM model incorporating shrinkage and double-weighted strategies for identifying cancer driver genes with functional impact.

BMC bioinformatics - 6 Mar 2024

Xu Xiaolu, Qi Zitong, Wang Lei, Zhang Meiwei, Geng Zhaohong, Han Xiumei

Abstract excerpt

BACKGROUND: Cancer, a disease with high morbidity and mortality rates, poses a significant threat to human health. Driver genes, which harbor mutations accountable for the initiation and progression of tumors, play a crucial role in cancer development. Identifying driver genes stands as a paramount objective in cancer research and precision medicine. RESULTS: In the present work, we propose a method for...

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Identifiers

PMID: 38448819
DOI: 10.1186/s12859-024-05707-8
PMCID: PMC10916024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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