Article
Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements.
Nucleic acids research - 16 Mar 2018
Watters Kyle E, Choudhary Krishna, Aviran Sharon, Lucks Julius B, Perry Keith L, Thompson Jeremy R
Abstract excerpt
In single stranded (+)-sense RNA viruses, RNA structural elements (SEs) play essential roles in the infection process from replication to encapsidation. Using selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq) and covariation analysis, we explore the structural features of the third genome segment of cucumber mosaic virus (CMV), RNA3 (2216 nt), both in vitro and in plant cell...
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