Article
Structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses.
RNA (New York, N.Y.) - 1 Jan 2021
Sherlock Madeline E, Hartwick Erik W, MacFadden Andrea, Kieft Jeffrey S
Abstract excerpt
Viruses commonly use specifically folded RNA elements that interact with both host and viral proteins to perform functions important for diverse viral processes. Examples are found at the 3' termini of certain positive-sense ssRNA virus genomes where they partially mimic tRNAs, including being aminoacylated by host cell enzymes. Valine-accepting tRNA-like structures (TLSVal) are an example that share some clear...
Topics
- Anticodon
- Base Sequence
- Binding Sites
- Computational Biology
- Genetic Variation
- Insect Viruses
- Models, Molecular
- Molecular Mimicry
- Phylogeny
- Plant Viruses
- RNA Folding
- RNA, Transfer, Val
- RNA, Viral
- Sequence Homology, Nucleic Acid
- Valine