Article

Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genomes Production

2024-07-15

Abstract excerpt

Chikungunya virus (CHIKV) is a mosquito borne RNA virus that poses an emerging threat to humans. As other RNA viruses, CHIKV encodes an error-prone RNA polymerase which, in addition to full-length genomes, gives rise to truncated, non-functional genomes coined defective viral genomes (DVGs). DVGs have been intensively studied in the context of therapy, as they can inhibit viral replication and dissemination in the...

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Literature Corpus work: 0de81121-c135-5e8b-ac33-7f84fa8d15a2
DOI: 10.20944/preprints202407.1212.v1

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