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Article

The RNA Architecture of the SARS-CoV-2 3′-Untranslated Region

21 Dec 2020

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. The 3′ untranslated region (UTR) of this β-CoV contains essential cis-acting RNA elements for the viral genome transcription and replication. These elements include an equilibrium between an extended bulged stem-loop (BSL) and a pseudoknot. The existence of such an equilibrium is supported by reverse...

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PMID: 33371200
DOI: 10.3390/v12121473

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