Article
Association of the Single Nucleotide Polymorphisms of the Genes Encoding IL-2 and IFN-γ With Febrile Seizure.
Acta medica Iranica - 1 Jun 2017
Shahrokhi Amin, Zare-Shahabadi Ameneh, Naeimi Poor Mohammad, Sajedi Firouzeh, Soltani Samaneh, Zoghi Samaneh, Shervin Badv Reza, Ashrafi Mahmoud Reza, Rezaei Nima
Abstract excerpt
Inflammatory elements and genetics have major roles in febrile seizures (FS) pathogenesis. Seventy patients were enrolled and compared with 139 controls. The allele and genotype frequency of the IL-2 gene at -330 and +166 positions and the IFN-γ at +874 position were determined. A significant positive association with GG genotype at position -330 in the patient group was found (P=0.003). Further, a positive...
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