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Article

Glucocorticoids Regulate the Vascular Remodeling of Aortic Dissection Via the p38 MAPK-HSP27 Pathway Mediated by Soluble TNF-RII.

EBioMedicine - 1 Jan 2018

Zhang Lei, Zhou Jian, Jing Zaiping, Xiao Yu, Sun Yudong, Wu Yani, Sun Huiying

Abstract excerpt

Increasing researches suggest that inflammatory response is involved in vascular remodeling, which plays an important role in the development of aortic dissection. Glucocorticoids have been widely used in the clinical practice due to its powerful and effective anti-inflammatory property. However, the potential relationship between glucocorticoids and aortic dissection was still obscure. This study sought to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to p38 Mitogen-Activated Protein Kinases

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Source

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Identifiers

PMID: 29287621
DOI: 10.1016/j.ebiom.2017.12.002
PMCID: PMC5828293

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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