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Article

Resource competition promotes tumour expansion in experimentally evolved cancer.

BMC evolutionary biology - 27 Dec 2017

Taylor Tiffany B, Wass Anastasia V, Johnson Louise J, Dash Phil

Abstract excerpt

BACKGROUND: Tumour progression involves a series of phenotypic changes to cancer cells, each of which presents therapeutic targets. Here, using techniques adapted from microbial experimental evolution, we investigate the evolution of tumour spreading - a precursor for metastasis and tissue invasion - in environments with varied resource supply. Evolutionary theory predicts that competition for resources within a...

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Identifiers

PMID: 29281983
DOI: 10.1186/s12862-017-1117-6
PMCID: PMC5745887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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