Article
The evolution of carrying capacity in constrained and expanding tumour cell populations.
Physical biology - 12 Aug 2015
Gerlee Philip, Anderson Alexander R A
Abstract excerpt
Cancer cells are known to modify their micro-environment such that it can sustain a larger population, or, in ecological terms, they construct a niche which increases the carrying capacity of the population. It has however been argued that niche construction, which benefits all cells in the tumour, would be selected against since cheaters could reap the benefits without paying the cost. We have investigated the...
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