Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer in light of experimental evolution.

Current biology : CB - 11 Sept 2012

Sprouffske Kathleen, Merlo Lauren M F, Gerrish Philip J, Maley Carlo C, Sniegowski Paul D

Abstract excerpt

Cancer initiation, progression, and the emergence of therapeutic resistance are evolutionary phenomena of clonal somatic cell populations. Studies in microbial experimental evolution and the theoretical work inspired by such studies are yielding deep insights into the evolutionary dynamics of clonal populations, yet there has been little explicit consideration of the relevance of this rapidly growing field to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Drug Resistance, Neoplasm
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Biological

Share to Mutagenesis

Share to Neoplasms

Share to Selection, Genetic

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 22975007
DOI: 10.1016/j.cub.2012.06.065
PMCID: PMC3457634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer in light of experimental evolution.PMID 22975007Read ↗

Clonal evolution in cancer.Semantic proximity Read ↗

The evolutionary theory of cancer: challenges and potential solutions.Semantic proximity Read ↗

The implications of clonal genome evolution for cancer medicine.Semantic proximity Read ↗

Genetic and non-genetic clonal diversity in cancer evolutionSemantic proximity Read ↗

The evolution of evolutionary processes in organismal and cancer evolution.Semantic proximity Read ↗

Somatic clonal evolution: A selection-centric perspective.Semantic proximity Read ↗

Measuring cancer evolution from the genome.Semantic proximity Read ↗

Immuno-oncology from the perspective of somatic evolution.Semantic proximity Read ↗

Cancer evolution: from Darwin to the Extended Evolutionary SynthesisSemantic proximity Read ↗

Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks.Semantic proximity Read ↗

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer.Semantic proximity Read ↗

A modelling framework for cancer ecology and evolution.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.